The Patent - Invention Magazine
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clinical trials

Medicine

Silver Diamine Fluoride Halts Childhood Cavities Without Drilling

A major multi-site clinical trial led by researchers at the University of Michigan has confirmed that painting teeth with silver diamine fluoride can arrest tooth decay in young children without drilling, injections, or sedation. The clinical discovery, published in JAMA Pediatrics, offers a low-cost medical innovation that could prevent severe dental pain and hospital surgeries for thousands of pediatric patients.

Giovanni Sapere

Medicine

Personalized mRNA Melanoma Vaccine Cuts Recurrence Risk by 42%

In an international Phase III trial, adding the personalized therapeutic vaccine intismeran to pembrolizumab immunotherapy reduced the risk of recurrence or death by 42% in high-risk melanoma patients after surgery. Presented at the ESMO Congress 2026, the findings establish a new therapeutic approach combining tailored neoantigen targeting with immune checkpoint blockade. This medical innovation offers post-surgical protection for patients facing high chances of cancer relapse.

Giovanni Sapere

Medicine

Nanorobots: What it is and how it works

Nanorobots are nanoscale devices designed to perform specific tasks within the human body, such as targeted drug delivery, repairing damaged tissue, or eliminating cancer cells. Thanks to their extremely small size, nanorobots can navigate through the circulatory system and directly penetrate…

Mattia Sapere